Correlates of Left Ventricular Global Longitudinal Strain and Surgical Intervention on Myocardial Bridges
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Myocardial Bridge of Coronary Artery
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Improvement of myocardial function and contractility
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
To examine the changes in left ventricular (LV) global longitudinal strain (GLS), using two-dimensional speckle tracking analysis, after left anterior descending (LAD) unroofing, in myocardial bridges (MBs) refractory to optimal medical therapy (OMT).
Detailed Description
The present study is enrolling all the MBs-patients who underwent angina surgical relief or medical treatment at the "Ospedali Riuniti" of Ancona, Italy, and the "University Hospital" of Chieti, Italy. All the participants will be examined utilizing echocardiography before and after the treatment. The two-dimensional speckle-tracking analysis will be performed with an off-line dedicated software from the apical 4-chambers-view. All the unroofing procedures will be performed under cardiopulmonary bypass.
Investigators
Francesco Bianco
Medical doctor
ITAB - Institute for Advanced Biomedical Technologies
Eligibility Criteria
Inclusion Criteria
- •Myocardial bridge of the anterior descending left coronary artery
Exclusion Criteria
- •Poor echocardiographic imaging quality
Outcomes
Primary Outcomes
Improvement of myocardial function and contractility
Time Frame: 1 to 6 month after the procedure/treatment optimizzation
The increment of global longitudinal strain analysis, from pre treatment values, as assessed by speckle-traking echocardiography
Secondary Outcomes
- Angina relief after surgical treatment(1-month)
- Improvement in quality of life(1-month)