Correlates of Left Ventricular Global Longitudinal Strain and Surgical Intervention on Myocardial Bridges
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Improvement of myocardial function and contractility
研究概览
简要总结
To examine the changes in left ventricular (LV) global longitudinal strain (GLS), using two-dimensional speckle tracking analysis, after left anterior descending (LAD) unroofing, in myocardial bridges (MBs) refractory to optimal medical therapy (OMT).
详细描述
The present study is enrolling all the MBs-patients who underwent angina surgical relief or medical treatment at the "Ospedali Riuniti" of Ancona, Italy, and the "University Hospital" of Chieti, Italy. All the participants will be examined utilizing echocardiography before and after the treatment. The two-dimensional speckle-tracking analysis will be performed with an off-line dedicated software from the apical 4-chambers-view. All the unroofing procedures will be performed under cardiopulmonary bypass.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Myocardial bridge of the anterior descending left coronary artery
排除标准
- •Poor echocardiographic imaging quality
结局指标
主要结局
Improvement of myocardial function and contractility
时间窗: 1 to 6 month after the procedure/treatment optimizzation
The increment of global longitudinal strain analysis, from pre treatment values, as assessed by speckle-traking echocardiography
次要结局
- Angina relief after surgical treatment(1-month)
- Improvement in quality of life(1-month)
研究者
Francesco Bianco
Medical doctor
ITAB - Institute for Advanced Biomedical Technologies