NCT03762538Unknown不适用
The Effect of the ALDH2 Gene Polymorphism on the Propofol Potency for Inducing Loss of Consciousness in Cardiac Patients: a Prospective Observational Study
Shanghai Zhongshan Hospital0 个研究点目标入组 100 人开始时间: 2019年2月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 主要终点
- Effect-site concentration
研究概览
简要总结
The aim of this study is to determine whether ALDH2 gene polymorphisms (G/G, G/A A/A) have effect on the potency of propofol.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •ASA III-IV
- •hepatic and renal insufficiency
研究组 & 干预措施
G/G group
Patients who are determined to be G/G genotype.
干预措施: Propofol (Drug)
G/A A/A group
Patients who are determined to be G/A or A/A genotypes.
干预措施: Propofol (Drug)
结局指标
主要结局
Effect-site concentration
时间窗: immediately after patient lose his/her consciousness
patient's effect-site concentration when he/she loss consciousness
次要结局
未报告次要终点
研究者
相似试验
Unknown
不适用
Association Between ALDH2 Gene Polymorphism and Atrial FibrillationAtrial FibrillationNCT05524142Second Affiliated Hospital, School of Medicine, Zhejiang University200
Unknown
不适用
The Relationship Between ALDH2 and Aortic DissectionAortic DissectionNCT02630212Qilu Hospital of Shandong University400
Unknown
不适用
A Validation Study of The Relationship Between ALDH2 and Aortic DissectionAortic DissectionNCT03780738Qilu Hospital of Shandong University200
招募中
不适用
The association between ADH1B and ALDH2 genotypes and the prognosis and effect of treatment in esophageal cancer patients.esophageal squamous cell carcinomaJPRN-UMIN000035369The Jikei University School of Medicine60
招募中
不适用
The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary SyndromePeripheral Artery Occlusive DiseaseAcute Coronary SyndromeNCT05078814Chimei Medical Center600