Peanut protein detection in serum

Completed

Conditions: intestinal permeability
Nutrient uptake
10025477
10001708

Registration Number: NL-OMON43466

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 10

Inclusion Criteria

- 20-35 year old males and females
- Body Mass Index (BMI) 18.5-25 kg/m2
- Suitable veins for blood sampling

Exclusion Criteria

- History of peanut allergy
- Known symptoms of immune disease, such as diabetes, gastritis, and coeliac disease.
- Known symptoms of intestinal disease, such as Crohn*s Disease, ulcerosis, and irritable bowel syndrome.
- Smoking
- Use of hard drugs
- Use of specific drugs: Chronic use of NSAIDs: aspirins, ibuprofen, etc.
- Drugs having an effect on gastric and/or intestinal function and motility, including antidepressants
- Participation in other scientific studies (with the exception of EetMeetWeet)
- Blood donation during the last six weeks before the start of the study

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary parameter of the pilot study is the number of subjects in which Ara<br /><br>h6 in serum can be detected with the sandwich ELISA after peanut consumption</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secundary parameter of this pilot study are serum factors that could<br /><br>possibly influence the sensitivity of the analysis method, such as total peanut<br /><br>IgE and IgG(4)</p><br>