comparison of two different methods of fluid management on function of kidney in patients undergoing surgery for kidney stones
Not Applicable
- Conditions
- Health Condition 1: N20- Calculus of kidney and ureter
- Registration Number
- CTRI/2018/12/016693
- Lead Sponsor
- niversity College of Medical Sciences and GTB Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Those patients who are scheduled for pcnl (percutaneous nephrolithotomy) surgery under general anaesthesia
Exclusion Criteria
patients <16 years and >65 years
Those receiving renal replacement therapy or with transplanted kidney or clinical evidence of significant dysrhythmia, cardiac failure,stroke, coronary heart disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of early postoperative AKI as defined by the KDIGO criteria (i.e., serum creatinine with/without urine output)Timepoint: Preoperative, 24 hours and 48 hours postoperatively. <br/ ><br>
- Secondary Outcome Measures
Name Time Method change in estimated GFR which will be calculated using MDRD equation.Timepoint: difference between serum creatinine values preoperatively as well as 24 hours and 48 hours postoperatively.;change in serum creatinine valuesTimepoint: difference between serum creatinine values preoperatively and postoperatively at 24 hours and 48 hours;severity of AKI as defined by KDIGO criteriaTimepoint: estimation of serum creatinine values preoperatively as well as 24 hours and 48 hours postoperatively <br/ ><br>urine output will be considered if estimates of hourly collection are available