Evaluation of the Effect of Oral fosfomycin Addition on Treatment of Patients with Klebsiella pneumoniae Carbapnemase Infections with Colisti

Phase 3

Recruiting

• Conditions: Klebsiella pneumoniae Carbapnemase Infections.; Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified elsewhere; B96.1

• Registration Number: IRCT20191104045328N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Patients with Klebsiella Pneumoniae Carbapenemase infection diagnosed by reliable culture and admitted to the infectious ward of Vali Asr Hospital are studied.

Exclusion Criteria

Allergy to fosfomycin
Patients with renal failure
Hemodialysis Patients
Under 12 years age
Patients who have received antibiotics affecting KPC for the past 72 hours.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eukocytosis. Timepoint: After a week of treatment. Method of measurement: Blood cell count.;Mute the fever. Timepoint: 24 hours / 48 hours / 72 hours / 96 hours / over 96 hours from start of treatment. Method of measurement: Using mercury thermometer orally or axillary.;Symptoms Remedy. Timepoint: 24 hours / 48 hours / 72 hours / 96 hours / over 96 hours from start of treatment. Method of measurement: Asking about the patient and the patient's status by observation.;Negative urine culture. Timepoint: After 72 hours of treatment. Method of measurement: urine culture test.