evofloxacin in treatment of tuberculosis infection of brain in childre
Phase 2
- Conditions
- Health Condition 1: A170- Tuberculous meningitis
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosed cases of tubercular meningitis presenting to Department of Pediatrics, All India Institute Medical Sciences, Rishikesh with a diagnosis of TB meningitis as per Marais’ criteria and parents willing to comply with the study protocol and follow up
Exclusion Criteria
Pre-existing major chronic systemic illness including cardiovascular (arrhythmia, prolonged QTc interval or history of any arrhythmia), respiratory (chronic lung disease), gastrointestinal system (chronic liver disease) or chronic renal disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Functional Status ScaleTimepoint: 12 weeks
- Secondary Outcome Measures
Name Time Method Childhood Behavioural Checklist internalizing, externalizing and total scoreTimepoint: 12 weeks;Duration of hospitalisationTimepoint: At diagnosis;Functional status scaleTimepoint: 12 weeks;Number of patients with paradoxical reactionTimepoint: within 12 weeks;Pediatric Cerebral Performance CategoryTimepoint: 12 weeks;Social quotient by Vineland Social Maturity ScaleTimepoint: 12 weeks;SurvivalTimepoint: 12 weeks