Comparison of the efficacy of a levofloxacin-tetracycline-based quadriple regimen with a clarithromycin-based regimen to eradicate Helicobacter pylori infectio

Phase 3

Recruiting

• Conditions: H pylori infection.; Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere; B96.81

• Registration Number: IRCT20200707048038N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 November 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

selection of patients based on clinical complaint of non-ulcer dyspepsia and endoscopy (confirmation of peptic ulcer or pathological confirmation of intestinal metaplasia or gastritis in the field of H. pylori) with a positive RUT test
no previous treatment for H. pylori infection
no use of quinolone and macrolide antibiotics during the last two months.
over 18 years of age.

Exclusion Criteria

Severe side effects of the drug that lead to discontinuation of the drug before completing one week of treatment

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of people with non-ulcer dyspepsia. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy.;Percentage of people with intestinal metaplasia. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy.;Percentage of people with peptic ulcer disease. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy.

Secondary Outcome Measures

Name	Time	Method
H-pylori eradication. Timepoint: after completing treatment. Method of measurement: Stool antigen test for H-pylori.;Drug side effect. Timepoint: every week. Method of measurement: according to patient.