Evaluation of the Effect of Pomegranate Peel Added Bread on Blood Sugar, Fats, and the Body's Defense Response
- Conditions
- Type 2 Diabetes
- Interventions
- Dietary Supplement: Pomegranate Peel
- Registration Number
- NCT05232305
- Lead Sponsor
- Toros University
- Brief Summary
The aim of this study is to evaluate the effects of the consumption of bread produced with the addition of pomegranate peels, which has a high antioxidant content, on blood glucose and lipid parameters, and some oxidant-antioxidant enzymes and lipid peroxidation in individuals with type 2 diabetes.
- Detailed Description
Between 01.02.2022 and 30.05.2022 with Specialist Dr. Emel SENOL's approval, by Specialist Dr. Akkız Zuhal ÖZTAŞ
The study will be conducted with 30 volunteers who present to the City Hospital Internal Medicine Polyclinic in Mersin.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
- Being diagnosed with type 2 diabetes for at least 5 years,
- Using only oral antidiabetic
- With a Body Mass Index (BMI) value ≥ 25.0 kg/m2,
- Signing the Informed Voluntary Consent Form,
- Being in an age range of 19-64 years.
- Having kidney, liver, and inflammatory diseases,
- Being on insulin therapy,
- Using prescription drugs and/or fiber supplements,
- Taking vitamin and mineral supplements,
- Being pregnant/lactating,
- Consuming excessive alcohol (>2 drinks/day),
- Being in the menstrual period,
- Receiving gluten enteropathy,
- Having allergy against pomegranate.
- In addition, individuals with Covid-19-related condition during the study process will be excluded from the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description People with type 2 diabetes who eat bread with pomegranate crust - Experimental Group Pomegranate Peel Individuals with type 2 diabetes who met the inclusion criteria and participated in the study will divided into two groups by Specialist Akkız Zuhal ÖZTAŞ and Specialist Doctor Emel ŞENOL, and they will be asked to consume the breads produced (in the preliminary study) produced as a standard (n=15) and with the addition of pomegranate peel (n=15) for eight weeks. The individuals participating in the study will be asked not to change their eating habits, physical activity habits, and drug treatments during the study period. Each individual participating in the study will be provided with the required amount of bread during the study and will be contacted weekly by Zeynep ÇAMLIK, a specialist dietitian, to verify whether they consume bread regularly.
- Primary Outcome Measures
Name Time Method Biochemical Blood Parameters First day at the beginning of the study Examination of between group differences regarding TBARS
Anthropometric Measurements - Weight First day at the beginning of the study Examination of between group differences regarding weight in kilogram
Anthropometric Measurements - Height First day at the beginning of the study Examination of between group differences regarding height in meter
Anthropometric Measurements - Body Mass Index First day at the beginning of the study Examination of between group differences regarding body mass index (BMI = weight in kilogram / height in meter 2)
Anthropometric Measurements - Waist Circumference First day at the beginning of the study Examination of between group differences regarding waist circumference in centimeters
Anthropometric Measurements - Hip Circumference First day at the beginning of the study Examination of between group differences regarding hip circumference in centimeters
- Secondary Outcome Measures
Name Time Method Biochemical Blood Parameters Eight weeks after the start of the study Comparison of between group differences regarding TBARS
Anthropometric Measurements - Weight Eight weeks after the start of the study Examination of between group differences regarding weight in kilogram
Anthropometric Measurements - Height Eight weeks after the start of the study Examination of between group differences regarding height in meter
Anthropometric Measurements - Body Mass Index Eight weeks after the start of the study Examination of between group differences regarding body mass index (BMI = weight in kilogram / height in meter 2)
Anthropometric Measurements - Waist Circumference Eight weeks after the start of the study Examination of between group differences regarding waist circumference in centimeters
Anthropometric Measurements - Hip Circumference Eight weeks after the start of the study Examination of between group differences regarding hip circumference in centimeters
Trial Locations
- Locations (1)
Özlem ÖZPAK AKKUŞ
🇹🇷Mersin, Yenişehir, Turkey