Spleen Stiffness Measurement as Predictor of High-risk Esophageal Varices in Patients with Cirrhosis and Hepatocellular Carcinoma

Recruiting

• Conditions: CirrhosisHepatocellular carcinomaEsophageal varicesPortal hypertension; Cirrhosis; Hepatocellular carcinoma; Esophageal varices; Portal hypertension

• Registration Number: TCTR20240722005
• Lead Sponsor: Khon Kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-22
• Last Update Posted: 19 August 2024
• Study Completion: 2025-05-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 41

Inclusion Criteria

Patient with liver cirrhosis
Patient with hepatocellular carcinoma

Exclusion Criteria

History of decompensated cirrhosis
Morbid obesity (BMI > 35 kg/m2)
Splenectomy
Splenic lesion (splenic mass/abscess)
Pacemaker or cardiac defibrillator implant patient
Known or suspect malignancy other than HCC
History of esophageal varices
History of Endoscopic variceal ligation
History of TIPS
Portal hypertension that not caused by cirrhosis and HCC
Hematologic disease with splenomegaly
Previous non-selective beta-blocker
Pregnancy or breast feeding
Severe infection
Heart disease (NYHA functional class III,IV)
COPD GOLD C or D
Chronic kidney disease stage IV, V

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Esophageal varices within 1 month after or before spleen stiffness measurement EGD

Secondary Outcome Measures

Name	Time	Method
Spleen stiffness within 1 month after or before EGD Spleen stiffness measurement