Treatment of multiple gingival recessions using volume-stable collagen-based gingival graft substitute impregnated with blood platelet derivative: a split-mouth randomized clinical trial

Not Applicable

• Conditions: Gingival recession; C07.465.714.354.750

• Registration Number: RBR-3hqrvrr
• Lead Sponsor: niversidade Federal de Santa Catarina

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-20
• Study Completion: 2022-08-31
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients requiring root coverage for multiple gingival recessions; of both sides of the mouth; in homologous teeth; in the maxillary aesthetic zone (between teeth 15 and 25); without interproximal involvement; with a minimum of three adjacent teeth in each side of the maxilla should present marginal recession at least one of them with a recession depth equal or over 3 millimeters; patients should be equal or over18 years-old; present good oral health.

Exclusion Criteria

Uncontrolled systemic or local conditions; diabetic volunteers; pregnant women; volunteers with periodontitis; smokers; volunteers with a history of mucogingival or periodontal surgery at surgical sites; prosthetic crowns at teeth or implants in the surgical sites; gingival recessions with less than 1 mm of keratinized tissue apical to recession areas.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in the recession depth measured in millimeters with clinical periodontal probe from gingival margin to cemento–enamel junction at the mid-buccal site before surgery and six months after root coverage.

Secondary Outcome Measures

Name	Time	Method
Improvement of the clinical parameters keratinized tissue width, bleeding on probing, probing depth, clinical attachment level, gingival thickness, and gingival phenotype measured with a periodontal probe before surgery and six months after root coverage.;Reduction on the patient-reported outcome measures such as discomfort, pain, swelling, bleeding, and ecchymosis, evaluated by a questionnaire.