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Serum Procalcitonin Level May Predict Acute Kidney Injury in ICU Patients With Sepsis

Completed
Conditions
Acute Kidney Injury
Interventions
Diagnostic Test: measure Serum procalcitonin level
Registration Number
NCT03097393
Lead Sponsor
Benha University
Brief Summary

The aim of this study is to examine if procalcitonin (PCT) can be used for early prediction of AKI septic patients in ICU.

Detailed Description

67 patients with sepsis were enrolled in this study. On admission, PCT was measured together with serum creatinine, urea, and other inflammatory markers. Quick Sepsis-related Organ Failure Assessment was calculated at the emergency department. Patients were classified into those with Acute kidney injury (AKI) and non-AKI groups.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
67
Inclusion Criteria
  • ICU patients with sepsis
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Exclusion Criteria
  • Patient known to have End-stage kidney disease
  • Patients on Renal replacement therapy
  • patients without procalcitonin level within 24 hours from admission.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Non-AKI groupmeasure Serum procalcitonin levelmeasure Procalcitonin among Patient did not develop Acute kidney injury during ICU stay
AKI GROUPmeasure Serum procalcitonin levelmeasure Procalcitonin among Patient developed Acute kidney injury during ICU stay
Primary Outcome Measures
NameTimeMethod
development of AKI28 Days

elevated kidney functions creatinine or oliguria

Secondary Outcome Measures
NameTimeMethod
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