Post Operative Pain Control: Morphine vs Fentanyl

Not Applicable

Completed

• Conditions: Post Operative Analgesia
• Interventions: Drug: Morphine; Drug: Fentanyl

• Registration Number: NCT02146638
• Lead Sponsor: Catholic University of the Sacred Heart

Brief Summary

Aim of this study is to compare benefits and disadvantages in using continuous infusion of morphine or fentanyl for post operative analgesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Study First Submitted: 2013-01-10
• Status Verified: 2014-05
• Study First Submitted QC: 2014-05-21
• Last Update Submitted: 2014-05-21
• Study First Posted: 2014-05-26
• Last Update Posted: 2014-05-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• ASA 1 or 2 patients
• undergoing major gynaecological surgery

Exclusion Criteria

• age > 60 years
• obesity (BMI>30 Kg/m2)
• cardiac and respiratory diseases
• renal impairment
• liver disorders
• allergies to any drug used in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Morphine	Morphine	Patients received morphine 0.02 mg/Kg/h infused at 2 ml/h for 24 hours. The infusion contained morphine and saline.
Fentanyl	Fentanyl	Patients received Fentanyl 0.3 mcg/Kg/h infused at 2 ml/h for 24 hours. The infusion contained morphine and saline.

Primary Outcome Measures

Name	Time	Method
pain scores	data were recorded during the 24 post operative hours	data were recorded at 1,6,18 and 24 hours after surgery

Secondary Outcome Measures

Name	Time	Method
analgesic requirements	during the 24 hours after surgery	if VAS value was equal or higher than 6 patients received ketorolac 30 mg iv

Trial Locations

Locations (1)

catholic University of the sacred Heart; 🇮🇹 Rome, Italy