Effectiveness of Diode low-level laser therapy on treatment of mucositis induced by chemoradiotherapy in H&N cancer patients referring to Guilan(Rasht) dental college:A single- blind randomized clinical trial

Phase 3

• Conditions: oral mucositis.; Oral mucositis (ulcerative)

• Registration Number: IRCT20180826040863N1
• Lead Sponsor: Rasht University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Head and neck cancer
Receiving Chemotherapy and Radiation Therapy
Getting oral mucositis stage3,4

Exclusion Criteria

Restricted opening of the mouth (less than 1cm2) that does not allow the use of laser on the tissue.
Relapse during treatment
Taking any medication to prevent and treat mucositis
Failure to perform mucositis treatment process
Inability to observe oral hygiene

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of pain. Timepoint: Laser: From the onset of the lesion / Day 4 ofTreatment / One week after treatment. mouthwash: From the beginning of the lesion for one month. Method of measurement: Based on the VAS index.;Severity of lesion. Timepoint: Laser: From the onset of the lesion / Day 4 ofTreatment / One week after treatment. mouthwash: weekly From the beginning of the lesion for one month. Method of measurement: Based on the WHO.;Length of treatment. Timepoint: Sum of Severity of Mucositis Severity of Days from the onset of symptoms of grade 3 and 4. Method of measurement: number of days.;Quality of life. Timepoint: Laser: From the onset of the lesion / Day 4 ofTreatment / One month after treatment. mouthwash:weekly From the beginning of the lesion for one month. Method of measurement: based on FACT_HN & OMWQ _ HN.