The effect of clonidine on pain post-tonsillectomy in childre

Phase 4

Recruiting

• Conditions: Pain following tonsillectomy surgery; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Surgery - Other surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12621001606875
• Lead Sponsor: Perth Children's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-25
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Children aged 4 – 16 years
Undergoing elective surgery under general anaesthesia for tonsillectomy +/- adenoidectomy +/- grommets or cautery of inferior turbinates
Staying overnight in hospital

Exclusion Criteria

Known cerebrovascular disease, heart failure, occlusive peripheral vascular disorders, such as Raynaud’s disease, cardiac arrhythmias
Known cardiovascular, respiratory or neurological disorders giving an ASA III or above status
Known hypersensitivity to the active substance or to any of the excipients listed Language barriers impeding data collection
Department for Child Protection and Family Support is involved in their care
Planned admissions to the Paediatric Intensive Care Unit (PICU)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure will be self-reported pain intensity using the Face Pain Scale – revised (FPS – R) [ Assessed 4 times daily for 7 days post tonsillectomy. <br>Parents/ patients will be asked to rate pain intensity twice in the morning and twice in the evening. At each time point the patients will be asked to rate their pain just before the meal (pain at rest) and then again with eating (pain on swallowing). ]