Randomized controlled trial of anti-stress effect of low-caffeine green tea on students during pharmacy practice

Not Applicable

• Conditions: Stress

• Registration Number: JPRN-UMIN000014942
• Lead Sponsor: niversity of Shizuoka

Brief Summary

We examined the anti-stress effect of green tea with lowered caffeine, low-caffeine green tea, on humans. The study design was a single-blind group comparison and participants (n=20) were randomly assigned to low-caffeine or placebo tea groups. To assess the anxiety of participants, the state-trait anxiety inventory test was used before pharmacy practice. The subjective stress of students was significantly lower in the low-caffeine-group than in the placebo-group during pharmacy practice. The level of salivary amylase activity, a stress marker, increased significantly after daily pharmacy practice in the placebo-group but not in the low-caffeine-group. These results suggested that the ingestion of low-caffeine green tea suppressed the excessive stress response of students.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-08-25
• Study Completion: 2014-09-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

Taking tranquilizer(s) Smoker Diagnosed as inadequate to participate in the study by a doctor

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Alteration in salivary amylase activity in students during pharmacy practice for 10 days.

Secondary Outcome Measures

Name	Time	Method
Physical condition, Sleeping time, State-trait anxiety inventory (STAI) test, Replying to a questionnaire (subjective stress, achievement emotion)