Profile-Related Evidence Determining Individualized Cancer Therapy in Pancreatic Cancer (PREDICT-PANC)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pancreatic Neoplasms
- Sponsor
- Medical College of Wisconsin
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Number of Subjects Receiving Targeted Therapy
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.
Investigators
Mandana Kamgar, MD
Assistant Professor
Medical College of Wisconsin
Eligibility Criteria
Inclusion Criteria
- •Age ≥18 years.
- •Pathologically confirmed pancreatic cancer.
- •Ability to understand a written informed consent document and the willingness to sign it
Exclusion Criteria
- •Age \<18 years.
- •Primary cancer diagnosis other than pancreatic cancer.
Outcomes
Primary Outcomes
Number of Subjects Receiving Targeted Therapy
Time Frame: 5 years
This measure is the number of study subject's whose treating physician prescribes and subsequently receives the therapeutic recommendation of the Molecular Tumor Board.