Investigation of the effect of anesthetic propofol on gene expression; Investigation of the effect of the anesthetic Isoflurane on gene expressio
Phase 3
Recruiting
- Conditions
- umbar spine injury.Injuries to the abdomen, lower back, lumbar spine and pelvis(S30-S39)S30-S39
- Registration Number
- IRCT20190121042444N5
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Patients who are candidates for elective surgery for posterior stabilization of the lumbar spine
ASA class I-II
Exclusion Criteria
Previous history of surgery
ASA class III or higher
Malignancies
Cardiovascular diseases
Chronic inflammatory diseases
Corticosteroid use
Emergency surgery
Any instability of the patient during surgery
Drug addiction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of mt-DNA. Timepoint: before the intervention and 1 hour after the operation and 1 day after the operation. Method of measurement: Measurement of serum levels in a blood test.;Duration of surgery. Timepoint: Surgery start time - surgery end time. Method of measurement: minutes.;Bleeding volume. Timepoint: End of surgery. Method of measurement: milliliter.;Complications of surgery. Timepoint: First of surgery- End of surgery. Method of measurement: Filling out the questionnaire.;Demographic information. Timepoint: The beginning of surgery. Method of measurement: Filling out the questionnaire based on the birth certificate information.
- Secondary Outcome Measures
Name Time Method