Trans-esophageal echocardiographic assessment of hepatic vasculature in patients undergoing living donor liver transplantation – A Prospective Observational study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To evaluate portal vein, hepatic vein and IVC flow velocities using TEE immediately after the reperfusion during live donor liver transplant surgery.
研究概览
简要总结
Liver transplantation is considered a standard of care and life-saving procedure for patients suffering from end-stage liver disease (ESLD). Due to cirrhotic cardiomyopathy, these patients usually have cardiac dysfunction which is not detected on routine testing but manifests during stress conditions of surgery. The expanding role of transesophageal echocardiography (TEE) in intraoperative monitoring is now increasing gradually and it is being used away from the context of cardiac surgeries alone. The American Association for anesthetists on liver diseases has recommended that TEE should be used for all orthotropic liver transplant cases. Similarly, the European association of echocardiography has also recommended for use of TEE in all liver transplant cases. TEE can be used not only to monitor cardiac changes but can also give valuable information about other organs such as the lungs and liver. In a case report by Khurmi et al, they used TEE to diagnose hepatic venous and IVC thrombus intra-operatively during liver transplant surgery. The anatomic proximity of the distal esophagus and gastric antrum to the hepatic vein, portal vein, and inferior vena cava make TEE an idol monitor for their proper assessment during liver transplant surgery. Hence, in this study, we aim to evaluate the hepatic vein, portal vein, and inferior vena cava by TEE during living donor liver transplant surgery.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •All patients undergoing living donor liver transplantation.
排除标准
- •Previous history of esophageal pathology like stricture, malignancy, diverticulum, laceration or history of previous esophageal surgery.
- •Esophageal varices > grade 2, gastric varices or active esophagitis.
- •History of recent upper gastro-intestinal bleed (within 1 month).
- •History of variceal banding within last month 5.
结局指标
主要结局
To evaluate portal vein, hepatic vein and IVC flow velocities using TEE immediately after the reperfusion during live donor liver transplant surgery.
时间窗: Baseline, 4 hours, 8 hours, 12 hours
次要结局
- To find out the angle on TEE at which portal vein, hepatic vein and ivc are seen(24 Hours)
- Any major finding on TEE during liver transplantation(24 Hours)
- Any complication related to TEE(48 Hours)
