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临床试验/NCT06981286
NCT06981286尚未招募不适用

Oral Health Parameter-Based Diabetes Type 2 Indication Using Machine Learning in Older Individuals With Mild Cognitive Impairment

Blekinge Institute of Technology1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2025年8月30日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
2,000
试验地点
1
主要终点
Detection perfomance

研究概览

简要总结

This study aims to explore the potential of using machine learning (ML) algorithms to predict Diabetes type2, based on oral health and demographic data. The objective is to evaluate the effectiveness of various ML models and identify the most relevant oral health indicators for predicting type 2 diabetes in individuals with mild cognitive impairment aged 60 and above.

详细描述

This cross-sectional study utilizes oral health and demographic data from the Swedish National Study on Aging and Care (SNAC-B). Participants aged 60 years or older with Mild Cognitive Impairment will be included in the analysis. The data will be used to develop and evaluate machine learning models for predicting type 2 diabetes.

Objectives:

  1. Primary Objective: To assess the potential of oral health parameters for binary classification of type 2 diabetes or not.
  2. Secondary Objective: To identify the most influential oral health parameters contributing to type 2 diabetes predictions.
  3. Tertiary Objective: To compare the performance of Random Forest (RF), Support Vector Machine (SVM), and CatBoost (CB) classifiers in predicting type 2 diabetes using oral health data.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Individuals aged 60 years or older.
  • •Participants with recorded oral health parameters with or without Diabetes type2

排除标准

  • •Individuals with Diabetes type1

结局指标

主要结局

Detection perfomance

时间窗: 12 months

Description: The study measures the classification performance of Machine Learning classifier. Performance metrics, Accuracy, precision, recall, F1-Score and confusion matrix will be used for the evaluation. The examination of the most important features relied on SHAP summary plots, providing visualizations of the influence of parameter groups on the output, organized by their importance. This importance is based on SHAP values, offering insights into features' effects on the ML model's decision-making process

次要结局

未报告次要终点

研究者

发起方
Blekinge Institute of Technology
申办方类型
Other
责任方
Sponsor

研究点 (1)

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