The Effectiveness of 5% hypertonic saline adjuvant to cervical epidural block in patients with cervical radicular pain screened for neuropathic pain using DN4 (Douler Neuropathique 4) questionnaire: a randomized controlled study
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0006031
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
1) Patients with chronic cervical unilateral radiating pain over 3 months
2) Patients with symptom-related unilateral 1-2 level lesions of the cervical spine in radiologic examination (CT or MRI)
3) Patients screened for neuropathic pain by obtaining 4 points or more in DN4 questionnaire
4) Patients whose symptoms have not improved even after conservative treatment for more than 3 months
5) Patients with pain intensity of NRS 4 or higher
6) 20 = age <80
7) Patients who voluntarily agreed in writing to participate in this clinical trial
1) Patients in acute phase with pain period less than 3 months
2) Patients whose pain intensity is less than 4 points or 10 points in NRS
3) When the axial pain is more severe than the radiating pain
4) Patients with progressive motor weakness or neurological findings
5) Those who are contraindicated in nerve block procedure, such as coagulopathy or infection
6) Patients with uncontrolled medical or psychiatric problems
7) Patients with side effects from local anesthetics, steroids, or contrast agents
8) Pregnant or lactating patients
9) Patients diagnosed with cancer and undergoing treatment
10) Patients with a history of surgery on the cervical spine
11) If the patient does not agree to participate in the study
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RS (Numerical rating scale, 0 = no pain, 10 = unbearable pain)
- Secondary Outcome Measures
Name Time Method RS (Numerical rating scale, 0 = no pain, 10 = unbearable pain);NDI (0 – 50; 0 = no disability, 50 = complete disability);MQS (Medication quantification scale);PHQ-9 (patient health questionnaire-9);GPE (Global perceived effect, 1-7);Responder rate (0 – 100% of patients)