Study Of Clinical Profile Of Spontaneous Bacterial Peritonitis And Its Variants In Cirrhosis

NEED OF STUDY 

SPONTANEOUS BACTERIAL PERITONITIS IS SERIOUS LIFE THREATENING COMPLICATION IN CIRRHOSIS .IT IS IMPORTANT TO RECOGNIZE SBP EARLY IN THE COURSE OF INFECTION BECAUSE THERE IS FRAQUENTLY A VERY SHORT WINDOW OF OPPORTUNITY DURING WHICH TO INTERVENE TO ENSURE A GOOD OUTCOME .IF OPPORTUNITY IS MISSED ,SHOCK ENSUES ,FOLLOWED RAPIDLY BY MULTI ORGAN FAILURE .

SURIVAL IS UNLIKELY IN PATIENTS WHO DEVELOP SHOCK PRIOR TO INITIATION OF ANTIBIOTICS..

ONE REPORT ESTIMATED THAT SURVIVAL DECREASED BY APPROXIMATELY 8 PERECENT FOR EACH HOUR DELAY IN STARTING ANTIBIOTICS IN PATIENTS WITH SEPTIC SHOCK .ANOTHER STUDY HD SHOWN THAT DELAYED PARACENTESIS IN PATIENTS WITH SBP LEADS TO 2.7 FOLD INCREASED RISK OF DEATH ;EACH HOUR OF DELAY IN PARACENTESIS IS ASSOSCIATED WITH 3.3 PERECENT INCREASE IN INHOSPITAL MORTALITY.THESE STATISTICS SIGNIFY NEED OF CLINICAL PROFILE OF SBPWHERE EARLY DIAGNOSIS MAKES BIG DIFFERENCE IN OUTCOMES .

DESCRIPTION OF STUDY

THE STUDY IS BASED ON PROSPECTIVE COLLECTION OF DATA FROM PATIENTS ADMITTED AT KASTURBA HOSPITAL ,MANIPAL ,DIAGNOSED WITH SPONTANEOUS BACTERIAL PERITONITIS IN CIRRHOSIS OF VARIOUS ETIOLOGIES CONFIRMED WITH CLINICAL FEATURES AND LABORATORY INVESTIGATIONS MEETING INCLUSION AND EXCLUSION CRITERIA AS MENTIONED ABOVE DURING STUDY PERIOD IN DEPARTMENT OF GENERAL MEDICINE AND DEPARTMENT OF GASTROENTEROLOGY .A PROFORMA IS PREPARED WHICH INCLUDES DEMOGRAPHIC DATA ,DETAILED HISTORYCLINICAL EXAMINATION AND REQUIRED INVESTIGATIONS AVAILABLE IN HOSPITAL ,DATA WOULD BE COLLECTED AND DOCUMENTED AFTER RECEIVING AFTER RECEIVING INFORMED WRITTEN CONSENT FROM THE PATIENT/PATIENT PARTY .PATIENT WITH INCOMPLETE DATA WILL BE DROPPED OUT OF STUDY.DATA WOULD BE ANALYSED USING APPROPRIATE STATISTICAL METHODS AND RESULTS WILL BE NOTED .