MedPath

Study on the development of children, whose mothers were treated for their anxious and/or depressed complaints during pregnancy.

Recruiting
Conditions
negative emotionsfetal programmingcognitive behaviour therapypregnancy outcomenegatieve emoties (angst en depressie)prenatale programmeringcognitieve gedragstherapiezwangerschapsuitkomst
Registration Number
NL-OMON29057
Lead Sponsor
niversity Medical Center Groningen
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
300
Inclusion Criteria

Having at least moderate depression and/or anxiety symptoms during pregnancy.

Exclusion Criteria

Women fulfilling one or more of the following criteria will be excluded from participation:

1. Multiparae pregnant women. We decided to exclude multiparae pregnant women as they have a markedly increased obstetric risk; inclusion will threaten the homogeneity of the study population and thereby decrease the sensitivity to detect effects;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Behavioral/emotional problems at age 1.5 as assessed by the total problems scale of the Child Behavior Check List 1.5 – 5 years. <br>
Secondary Outcome Measures
NameTimeMethod
1. Mental, psychomotor and behavioral development of the child at age 18 months according to the Bayley scales;<br /><br>2. Maternal anxiety and depression during pregnancy and 6 weeks postnatal;<br /><br>3. Maternal attachment style;<br /><br>4. Neonatal outcomes: birth weight, gestational age and Apgar score;<br /><br>5. Health care consumption and general health status (economic evaluation). <br>
© Copyright 2025. All Rights Reserved by MedPath