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Clinical Trials/NCT06238180
NCT06238180
Withdrawn
Not Applicable

Prediction of Sepsis in Patients Undergoing Abdominal Surgery: A Prospective, Observational Clinical Study

Aisthesis Medical P.C.2 sites in 1 country55 target enrollmentNovember 29, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sepsis
Sponsor
Aisthesis Medical P.C.
Enrollment
55
Locations
2
Primary Endpoint
Accuracy of AI-Driven Sepsis Prediction in Postoperative Period
Status
Withdrawn
Last Updated
23 days ago

Overview

Brief Summary

The goal of this prospective observational study is to develop and utilize an Artificial Intelligence (AI) model for the prediction of postoperative sepsis in patients undergoing abdominal surgery. The main questions it aims to answer are:

  1. Can a remote AI-driven monitoring system accurately predict sepsis risk in postoperative patients?
  2. How effectively can this system integrate and analyze multimodal data for early sepsis detection in the surgical ward?

Participants are equipped with non-invasive PPG-based wearable devices to continuously monitor vital signs and collect high-quality clinical data. This data, along with demographic and laboratory information from the Electronic Health Record (EHR) of the hospital, are used for AI model development and validation.

Registry
clinicaltrials.gov
Start Date
November 29, 2023
End Date
June 30, 2024
Last Updated
23 days ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Aisthesis Medical P.C.
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing elective abdominal surgery.
  • Postoperative admission to the surgical ward.
  • Age 18 years or older, who are able and willing to participate and have given written consent.
  • On admission, the primary investigator assess their risk to deteriorate during the first 72 hours after admission as reasonably high.

Exclusion Criteria

  • \<18 years of age Known allergy or contraindication to the monitoring devices.
  • Pre-existing conditions that could interfere with the study (e.g., chronic sepsis, immunodeficiency disorders).
  • Day case surgery.
  • Pregnancy.
  • Immediate transfer to ICU postoperatively.
  • Patient refusal or unable to give written consent.

Outcomes

Primary Outcomes

Accuracy of AI-Driven Sepsis Prediction in Postoperative Period

Time Frame: The accuracy of sepsis prediction will be assessed from the day of surgery, assessed daily for up to 7 days post-surgery or until hospital discharge.

This primary outcome measure evaluates the accuracy of an AI-driven monitoring system in predicting postoperative sepsis among patients undergoing abdominal surgery. The measure focuses on the system's ability to correctly identify sepsis, considering sensitivity, specificity, and predictive values.

Study Sites (2)

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