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Clinical Trials/NCT05697978
NCT05697978
Recruiting
Not Applicable

Distance and Intermediate Visual Acuity in Patients With Implanted Monofocal Negative Aspheric Intraocular Lens

Faculty Hospital Kralovske Vinohrady3 sites in 1 country100 target enrollmentOctober 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intraocular Lens
Sponsor
Faculty Hospital Kralovske Vinohrady
Enrollment
100
Locations
3
Primary Endpoint
Monocular corrected Distance Visual Acuity (CDVA)
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

To get the visual outcomes for distance and intermediate and binocular defocus curve in patients with implanted monofocal intraocular lens Clareon (IOL; model SY60CL; Alcon Vision LLC) at 3 months after the surgery.

Detailed Description

The goal of refractive cataract surgery is to remove the opacity, or cataract and to produce the desired refractive outcome. In most cases, the desired outcome is an emmetropic eye, or an eye that sees 20/20 Snellen for distance vision post-surgery with the implant of a monofocal IOL. This, however, does not offer much in the way of intermediate and near vision. The increased desire for simultaneous distance, intermediate and near vision has increased the popularity of multifocal IOLs (MIOLs). However MIOLs provide visual acuity for all distances, they has occurence of optical phenomena such as glare and halo and lower contrast sensitivity. Extended depth of focus (EDOF) lens should provide distance vision as good as monofocal lens and intermediate vision better than monofocal but without or with less appearance of optical phenomenon or decreased contrast sensitivity. This study is prospective, multi-center, conducted from 10/2022 to 08/2023 in the Ophthalmology department of Faculty Hospital Kralovske Vinohrady in Prague, in Eye Center Prague and Eye Clinic SOMICH (Karlovy Vary). The research protocol was explained to all participants and informed consent was signed before enrolling patient to the study. The study was approved by the Ethics Committee of Faculty Hospital Kralovske Vinohrady and will enrolled up to 100 patients with presence of cataract in both eyes. Bilateral clear corneal phacoemulsification and IOL implantation is performed by two experienced surgeon using the same technique in both eyes. The surgical process involved topical anesthesia, superior 3-step clear corneal incision (2,2mm), 5,0mm curvilinear capsulorhexis, phacoemulsification, bilateral irrigation- aspiration and implantation of monofocal aspheric intraocular lens (Clareon Alcon vision LLC). Patients are scheduled for visit at 3 months after the surgery.

Registry
clinicaltrials.gov
Start Date
October 1, 2022
End Date
August 1, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Faculty Hospital Kralovske Vinohrady
Responsible Party
Principal Investigator
Principal Investigator

Andrea Janekova

Principal Investigator

Faculty Hospital Kralovske Vinohrady

Eligibility Criteria

Inclusion Criteria

  • presence of cataract in both eyes
  • no other ocular pathology affecting visual acuity
  • bilateral phacoemulsification cataract surgery was arranged for both eyes
  • corneal astigmatism up to 0,5 cylinder (measured by IOL Master biometry)
  • dioptric power of both selective lens within 1,5 D range in one patient
  • selecting IOL power between 15 D and 28 D power range

Exclusion Criteria

  • complicated cataract
  • corneal opacities or irregularities
  • amblyopia
  • anisometropia
  • coexisting ocular pathologies
  • history of ocular surgery
  • refusal or unable to maintain follow-up

Outcomes

Primary Outcomes

Monocular corrected Distance Visual Acuity (CDVA)

Time Frame: 3 months

Monocular corrected distance visual acuity (CDVA) is measured at 4 m using an ETDRS (Early Treatment Diabetic Retinopathy Study) illumination cabinet (Precision Vision) under photopic conditions.

Binocular corrected Distance Visual Acuity (CDVA)

Time Frame: 3 months

Binocular corrected distance visual acuity (CDVA) is measured at 4 m using an ETDRS (Early Treatment Diabetic Retinopathy Study) illumination cabinet (Precision Vision) under photopic conditions.

Monocular distance corrected intermediate visual acuity (DCIVA)

Time Frame: 3 months

Monocular distance corrected intermediate visual acuity is measured using printed ETDRS charts for distance of 66cm

Binocular uncorrected intermediate visual acuity (UIVA)

Time Frame: 3 months

Binocular intermediate visual acuity is measured using printed ETDRS charts for distance of 66cm

Binocular distance corrected intermediate visual acuity (DCIVA)

Time Frame: 3 months

Binocular distance corrected intermediate visual acuity is measured using printed ETDRS charts for distance of 66cm

Monocular uncorrected intermediate visual acuity (UIVA)

Time Frame: 3 months

Monocular intermediate visual acuity is measured using printed ETDRS charts for distance of 66cm

Secondary Outcomes

  • Binocular defocus curve(3 months)

Study Sites (3)

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