Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery

Completed

• Conditions: Basal Cell Carcinoma; Squamous Cell Carcinoma

• Registration Number: NCT00793169
• Lead Sponsor: Northwestern University

Brief Summary

The primary objective of this study is to (1) determine whether local injection of lidocaine used during Mohs surgery will elevate serum lidocaine concentrations to a level that could cause systemic symptoms and (2) determine whether sustained high levels of serum lidocaine occur after intralesional anesthesia on the face and neck. This study is a cross-sectional study of 10 subjects with basal cell carcinoma or squamous cell carcinoma of the face or neck requiring Mohs micrographic surgery. The study will consist of a brief questionnaire and blood draws during their Moh's surgical procedure.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Study First Submitted: 2008-11-17
• Study First Submitted QC: 2008-11-18
• Study First Posted: 2008-11-19
• Results First Submitted: 2010-09-30
• Results First Submitted QC: 2010-10-29
• Results First Posted: 2010-11-30
• Status Verified: 2021-12
• Last Update Submitted: 2021-12-02
• Last Update Posted: 2021-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Number of Subjects With Detectable Serum Lidocaine Concentrations (<0.1 ug/mL) at Each Blood Draw.	6 hours

Trial Locations

Locations (1)

Northwestern University; 🇺🇸 Chicago, Illinois, United States