Effects of common topical glaucoma therapy on optic nerve head blood flow autoregulation during increased arterial blood pressure and artificially elevated intraocular pressure in healthy humans

Department of Clinical Pharmacology, Medical University of Vienna0 sites54 target enrollmentJanuary 5, 2006

Overview

No summary available.

Registry

who.int

Start Date

January 5, 2006

End Date

TBD

Last Updated

12 years ago

Study Type

Interventional clinical trial of medicinal product

Sex

Male

Sponsor

Department of Clinical Pharmacology, Medical University of Vienna

•54 healthy male subjects
•Men aged between 19 and 35 years, nonsmokers
•\-Body mass index between 15th and 85th percentile (Must et al. 1991\)
•\-Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
•\-Normal ophthalmic findings, ametropy \< 1 Dpt.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range
•F.1\.3 Elderly (\>\=65 years)

•\-Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
•\-Treatment in the previous 3 weeks with any drug
•\-Symptoms of a clinically relevant illness in the 3 weeks before the first study day
•\- Blood donation during the previous 3 weeks
•\- Presence of intraocular pathology: ocular hypertension, glaucoma, retinal vasculopathy or other retinal diseases