A Case-control Study on the Impact of Genetic Polymorphisms on Dental Implant Loss.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- genetic polymorphisms associated with implant loss
研究概览
简要总结
Patients that may participate in this case-control study underwent dental implant surgery in the University Hospital in Ghent in 2004-2007.
According to one of our recent papers based on this patient group, 34/461 patients lost one or more implants. The goal is to invite these 34 patients, to update the anamnesis, to perform a brief clinical oral examination and to have a blood sample. The latter is necessary to identify relevant genetic polymorphisms of the patient that are associated with implant loss. Among the remaining patients that did not lose implants, another 34 'controls' will be invited for the same examinations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Dental implant surgery in the University Hospital in Ghent in 2004-
- •Case: dental implant loss
- •Control: no dental implant loss
排除标准
- 未提供
研究组 & 干预措施
CONTROL: no dental implants lost
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, who did not lose their implants.
干预措施: oral examination (Procedure)
CONTROL: no dental implants lost
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, who did not lose their implants.
干预措施: Blood sample (Procedure)
CASE: patients lost one or more implants
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, but who lost one or more implants.
干预措施: Blood sample (Procedure)
CONTROL: no dental implants lost
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, who did not lose their implants.
干预措施: anamnesis (Other)
CASE: patients lost one or more implants
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, but who lost one or more implants.
干预措施: anamnesis (Other)
CASE: patients lost one or more implants
Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, but who lost one or more implants.
干预措施: oral examination (Procedure)
结局指标
主要结局
genetic polymorphisms associated with implant loss
时间窗: after 3 to 6 years
Identification of genetic polymorphisms that are associated with implant loss. It concerns only one evaluation (1 blood sample).
次要结局
未报告次要终点