Probiotics in the treatment of Helicobacter Pylori infectio
- Conditions
- helicobacter pylori infection.Helicobacter pylori [H.pylori] as the cause of diseases classified
- Registration Number
- IRCT201201218793N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 66
more than 2 and less than 14 years of age; gastrointestinal symptoms including epigastric tenderness, abdominal pain at night, worsening of abdominal pain by eating, early satiety, abdominal pain or weight loss without a known cause, frequent vomiting and Iron deficiency anemia; confirmation of Helicobacter Pylori infection by rapid urease test or histopathology.
Exclusion criteria: use of proton pump inhibitors, H2 receptor antagonists, bismuth compounds and antibiotics in the past 4 weeks; history of surgery on the stomach; sensitivity to certain types of antibiotics; G6PD enzyme deficiency(in these patients the use of furazolidone may lead to anemia ); known underlying disease including renal failure, heart disease or endocrine disease.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradication rate of helicobacter pylori. Timepoint: after two months of the treatment. Method of measurement: stool antigen for helicobacter pylori.
- Secondary Outcome Measures
Name Time Method Endoscopic finding. Timepoint: at the time of endoscopy. Method of measurement: by the report of the person performing the endoscopy.;Adverse effects of the drugs. Timepoint: during the course of treatment. Method of measurement: subjective /asking the patients and parents.;Concordance of the result of rapid urease test and pathology report. Timepoint: after the pathology report is prepared. Method of measurement: The comparison of the result of urease test with histopathological report by the researchers.