Study of Reserves After Traumatic Brain Injury

Not Applicable

Brief Summary: It is hypothesized that the long-term results of rehabilitation and subsequent aging after Brain Trauma depend on brain's premorbid anatomical (structural) and functional (cognitive, emotional) reserves.

The purpose of this study are:

1. to determine whether such reserves exist.

2. to study their convergent and discriminant validity.

3. to study their characteristics.

Recruitment & Eligibility

Inclusion Criteria

Moderate-Severe Traumatic Brain Injury according to at least 1 the following:
- Duration of loss of consciousness (LOC) - more then 1/2 hour
- Glasgow Coma Scale (GCS) - less then 13
- Post Traumatic Amnesia (PTA) - more then 24 hours.
At least 1 year after the injury.

Exclusion Criteria

Mild Traumatic Brain Injury
the present state of Post Traumatic Amnesia
dementia
the age less than 18 years on the moment of injury
less than 1 year since the injury
incapacity of the patient to cooperate in the study (incapacity of any source including physical, mental, and language problems)
premorbid diagnosis of Mental Retardation

Arm && Interventions

Group	Intervention	Description
healthy persons	Brain MRI	-
healthy persons	MRI	-
patients after moderate-severe TBI	Brain MRI	-
patients after moderate-severe TBI	MRI	-

Primary Outcome Measures

Name	Time	Method
Neuropsychological battery	neuropsychological baterry for every participant will be performed during 3-4 meetings. An expected average for complete neuropsychological assessment is about 8 weeks

Secondary Outcome Measures

Name	Time	Method

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