Perioperative glutamine administration: a potential therapy for preventing post-operative immune hypo-responsiveness

Not Applicable

Completed

• Conditions: Post-operative immune hypoparesis in children undergoing major surgery; Surgery

• Registration Number: ISRCTN86556841
• Lead Sponsor: The Institute of Child Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-06-15
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

96 Children undergoing major surgery at Great Ormond Street Hospital, London. Patients included will be minimised into the following groups of operations
thoracotomy for oesophageal or lung surgery: Nissen fundoplication; laparotomy for intestinal obstruction; colectomy

Exclusion Criteria

Patients with pre-existing infection, multi-organ dysfunction syndrome, congenital immune deficiency and congenital or acquired severe liver dysfunction (Child's C) will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified