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Clinical Trials/NCT00967200
NCT00967200CompletedNot Applicable

Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis

University Hospital, Montpellier2 sites in 1 country180 target enrollmentStarted: November 2003Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
180
Locations
2
Primary Endpoint
Pathophysiology of gliomas

Study Overview

Brief Summary

RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.

Detailed Description

OBJECTIVES:

Primary

  • To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches.

Secondary

  • To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to 120 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Pathophysiology of gliomas

Time Frame: 1 day

Pathophysiology of gliomas that may predict prognosis and progression or that could identify new therapeutic

Secondary Outcomes

  • Identification of molecular(1 day)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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