Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Central Nervous System Lymphoma
- Sponsor
- University Hospital, Montpellier
- Enrollment
- 180
- Locations
- 2
- Primary Endpoint
- Pathophysiology of gliomas
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.
Detailed Description
OBJECTIVES: Primary * To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches. Secondary * To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy. OUTLINE: This is a multicenter study. Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Pathophysiology of gliomas
Time Frame: 1 day
Pathophysiology of gliomas that may predict prognosis and progression or that could identify new therapeutic
Secondary Outcomes
- Identification of molecular(1 day)