A comparison of hemodynamic changes between Etomidate vs Propofol as induction agents during intubation in ICU A Randomised Control Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- To study the effect of the two induction agents-propofol and etomidate on haemodynamic instability like cardiovascular collapse or respiratory failure in ICU subjects.
研究概览
简要总结
Participants undergoing intubation, hemodynamic variations with each induction agent, any advert peri-intubation event will be documented and compared. Hemodynamic variations caused by the drugs plays an important role in determining the peri-intubation mortality and morbidity. We also hypothesized here that the identification of modifiable variables can have an impact on the participant’s outcome and help to mitigate the incidences and severity of peri-intubation cardiovascular collapse.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Age more than 18 yrs of either sex admitted in ICU requiring endotracheal intubation.
排除标准
- •1.Age less than 18yrs requiring endotracheal intubation
- •Post cardiac arrest patients
- •Contraindications to Propofol or Etomidate
- •Known pregnancy
- •Lack of equipoise.
结局指标
主要结局
To study the effect of the two induction agents-propofol and etomidate on haemodynamic instability like cardiovascular collapse or respiratory failure in ICU subjects.
时间窗: Outcome observed at time interval of 1minute, 5 minutes, 15 minutes and 30 minutes.
次要结局
- 1.Ease of Intubation Score(2.Change in oxygenation status)
研究者
DR SURAVI SAMANTA
FORTIS ESCORTS HOSPITAL, FARIDABAD, HARYANA