IRCT20210524051384N10招募中Unknown
Effect of add-on therapy with Ranolazine on reducing tissue ischemia and improvement of clinical outcome in patients with severe burn: A clinical trial
Rasht University of Medical Sciences0 个研究点目标入组 78 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 78
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •Age range from 18 to 65 years
- •Acute burn in less than 6 hours
- •Total body surface area (TBSA) between 20 - 50%
- •patients of American Society of Anesthesiologists (ASA) class I (a normal healthy person)
- •Fill out the informed consent
排除标准
- •Having severe hypertension blood pressure (BP) = 160/90 mmHg or systolic pressure below 100 mmHg
- •Ischemic changes in electrocardiogram (ECG)
- •Heart rate less than 70 beats per minute
- •Pregnant women
- •Peripheral vascular disease
- •Presence of inhalation injury
- •Presence of burn shock (including decreased cardiac output, increased vascular resistance, hypovolemia and hypoperfusion following severe burns)
- •Electrical and chemical burns
- •Kidney or liver failure caused by burns (according to the kidney and liver metabolism of the drug)
- •Presence of drug interactions with the patient's previous medications
研究者
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