A study for decreasing effects of yogurt containing Lactobacillus gasseri PA-3 on the serum uric acid levels
- Conditions
- Healthy adult
- Registration Number
- JPRN-UMIN000024866
- Lead Sponsor
- ihonbashi Kakigara Cho Clinic
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 240
Not provided
1) Subjects who are instructed pharmacotherapy for hyperuricemia or gout or life guidance by physician 2) Subjects who have the past medical history of gout 3) Subjects who routinely take Meiji Probio Yogurt PA-3 4) Subjects who routinely take health food effective for reducing serum uric acid levels 5) Subjects who routinely intensive exercises 6) Among subjects who have or have a history of urinary tract infections, liver diseases, heart diseases, urolithiasis, renal disorders, hypertension, diabetes mellitus, subjects who are undergoing pharmacotherapy or who are planning to receive pharmacotherapy during the study 7) Subjects who are routinely unbalanced on dietary habits 8) Subjects who show allergic responses to dairy products 9) Subjects who have participated in other clinical tests within the past one month 10) Subjects who were judged inadequate by investigator for other reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum uric acid level and change
- Secondary Outcome Measures
Name Time Method 1) AST(GOT), ALT(GPT),gamma-GTP, ALP, LDH, total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride , urea nitrogen, serum creatinine, blood sugar, HbA1c, Na, Cl, K and change 2) urine creatinine, urine uric acid and change 3) body weight, BMI and change 4) blood pressure, pulse rate and change 5) the amount of urinary excretion of uric acid, uric acid clearance, creatinine clearance, the rate of urinary excretion of uric acid and change