Investigation of Heart Failure Status Over Time Using Respiratory Parameters

Completed

• Conditions: Heart Failure, Congestive; Sleep Apnea Syndromes

• Registration Number: NCT00494117
• Lead Sponsor: ResMed

Brief Summary

The purpose of the study is to investigate respiratory indicators for clinically important changes in Heart Failure status over time.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-06
• Study First Submitted: 2007-06-28
• Study First Submitted QC: 2007-06-28
• Study First Posted: 2007-06-29
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2010-07
• Last Update Submitted: 2010-07-25
• Last Update Posted: 2010-07-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Moderate to severe Heart Failure (as determined by Echocardiogram or by treating physician)

Exclusion Criteria

• Malignant disease affecting gas exchange or respiratory parameters
• Medications compromising breathing with no adverse affects on heart failure
• Clinically significant (moderate to severe) asthma requiring therapy
• Chronic parenchymal lung disease (FEV1/FVC ratio = 65% or as determined by the treating physician)
• Severe pulmonary hypertension
• Heart failure due to alcohol abuse or chemotherapy
• Narcotic abuse/intravenous drug use (including HIV+ and hepatitis C)
• Alcohol consumption > 80g/day
• Patients receiving home Oxygen
• Methicillin- resistant Staphylococcus aureus infection
• Narcolepsy
• Cataplexy
• Enrolled in any concurrent study, that may confound the results of this study.
• Inability or refusal to sign the Patient Consent Form
• Inability or refusal to adhere to protocol requirements

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Royal Prince Alfred Hospital; 🇦🇺 Camperdown, New South Wales, Australia