ITMCTR1900002583
Recruiting
Phase 1
Psychological and Neural Mechanisms of Specific and Non-Specific Effects of Acupuncture in Knee Osteoarthritis
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine0 sitesTBD
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged 45\-65 years, male or female;
- •2\. Knee pain more than 6 months;
- •3\. KL (Kellgren\-Lawrence) grade II or III in recent 12 months;
- •4\. NRS \>\= 4 in the past one week;
- •5\. Right handedness;
- •6\. Signed informed consent.
Exclusion Criteria
- •1\. Surgery history of knee or waiting for surgery (knee replacement or knee arthroscopy);
- •2\. History of arthroscopy within 1 year or intra\-articular injection within 6 months;
- •3\. Knee pain caused by other diseases (such as joint bodies, severe effusion of joint cavity, infection, malignant tumors, autoimmune diseases, trauma, etc.);
- •4\. Severe acute/chronic organic or mental diseases;
- •5\. Coagulation disorders (such as hemophilia, etc.);
- •6\. Pregnant women, pregnant and lactating women;
- •7\. Claustrophobia or with a cardiac pacemaker, metal products and other contraindicated by MRI examinations;
- •8\. Severe skull anatomical asymmetry or definite lesions were found in magnetic resonance scanning;
- •9\. History of receiving acupuncture or massage treatment within 1 months;
- •10\. Allergy to needles and alcohol, or fear acupuncture needles;
Outcomes
Primary Outcomes
Not specified
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