Study on early warning of cerebral infarction risk and intervention mechanism of ''Xing-Nao Kai-Qiao'' acupuncture method

Phase 1

Recruiting

• Conditions: cerebral infarction

• Registration Number: ITMCTR2100004937
• Lead Sponsor: The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Aged 40 to 80 years;
2.The first onset of acute ischemic stroke patients, or have a history of ischemic stroke, but the National Institute of Health Stroke Scale (NIHSS) is less than 4 points, and within 48 hours of onset, through history, physical examination, CT or MRI examination confirmed the existence of acute ischemic stroke;
3.The patients agreed to accept the protocol and signed the informed consent;
4.Patients can cooperate with the collection and preservation of medical history data and the follow-up process in the future.

Exclusion Criteria

1. Patients with needle sickness;
2. Patients with history of intracranial hemorrhage or subarachnoid hemorrhage;
3. Atrial fibrillation and other cardiogenic acute ischemic stroke patients;
4. End stage patients with severe disability or disease;
5. There were severe heart, liver and kidney dysfunction, total bilirubin > 1.5 times of the upper limit of normal value, aspartate aminotransferase (AST) or alanine aminotransferase (ALT) > 2.5 times of the upper limit of normal value;
6. Patients with pulmonary infection or severe systemic infection;
7. Other brain organic diseases cause intracranial hypertension, such as brain tumors;
8. Patients with HIV positive, syphilis antibody positive, hepatitis B, hepatitis C or other serious infectious diseases;
9. Patients with severe mental illness, cognitive impairment or inability to understand and sign informed consent;
10. Patients with metabolic diseases such as diabetes, hyperthyroidism or hypothyroidism, gout, etc;
11. Patients who participated in other clinical studies within 3 months;
12. Patients who have experienced surgery or trauma (including fracture) in the past month.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ational Institutes of Health Stroke Scale;Metabolomics detection;

Secondary Outcome Measures

Name	Time	Method
Efficacy criteria;Barthel index of activities of daily living;Modified Rankin scale;