French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis
- Conditions
- Quality of Life
- Interventions
- Other: Procedure surgery behavioral and genetic diagnosisProcedure: quality of life after different type of surgery
- Registration Number
- NCT01987518
- Lead Sponsor
- Hôpital Edouard Herriot
- Brief Summary
French cohorte about polyposis digestive diseases
- Detailed Description
Family Adenomatous Polyposis APC and MYH Genes Peutz Jeghers Disease Cowden Disease Festooned polyposis Juvenile polyposis Hyperplastic polyposis
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 350
Inclusion Criteria
- APC Gene mutation
- MYH Homozygote mutation
- COWDEN Disease with PTEN gene mutation
- Peutz Jeghers Disease with STK 11 gene mutation
- Juvenile polyposis with SMAD 4 gene mutation
Exclusion Criteria
- heterozygote MYH Gene Mutation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description digestive polyposis Procedure surgery behavioral and genetic diagnosis Family adenomatous polyposis (APC or MYH genes) Peutz Jeghers Disease Cowden Disease Festooned Polyposis Juvenile Polyposis Hyperplastic Polyposis digestive polyposis quality of life after different type of surgery Family adenomatous polyposis (APC or MYH genes) Peutz Jeghers Disease Cowden Disease Festooned Polyposis Juvenile Polyposis Hyperplastic Polyposis
- Primary Outcome Measures
Name Time Method genetic diagnosis or over 50 polyps in the stomach in the duodenum or in the colon 10 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hopital Edouard Herriot
🇫🇷Lyon, Rhone Alpes, France