The effect of remifentanil - thiopental sodium on cognitive impairment after electroconvulsive therapy
Not Applicable
- Conditions
- Patient with psychiatric disorder.Mental and behavioural disorders due to psychoactive substance use,Schizophrenia, schizotypal and delusional disorders,Mood [affective] disordersF10-39
- Registration Number
- IRCT201306086280N2
- Lead Sponsor
- Guilan University of Medical Sciences,Research and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
patients with psychiatric disorders diagnosed by psychiatrists according to DSMIV-TR criteria; age between 18-60 years old; signing informed consent; ASA physical status I or II; ECT candidates for the first time.
Exclusion criteria: emergency ECT; severe cognitive dysfunction prior to ECT; history of mental retardation; severe heart disease; history of previous ECT; ASA physical status III-IV; uncontrolled hypertension and needs to treat agitation after ECT.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of cognitive impairment after electroconvulsive therapy in general anesthesia with remifentani plus thiopental sudium. Timepoint: Before ECT, 5 hours and 24 hours after ECT. Method of measurement: By testing mini mental status exam (MMSE).;Severity of cognitive impairment after electroconvulsive therapy in general anesthesia with remifentani plus thiopental sudium. Timepoint: Before ECT, 5 hours and 24 hours after ECT. Method of measurement: By testing mini mental status exam (MMSE).
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: Before induction of anesthesia, immediately after ECT, after entering the recovery. Method of measurement: By electronic sphygmomanometer in the ECT room.;Heart rate. Timepoint: Before induction of anesthesia, immediately after ECT, after entering the recovery. Method of measurement: By monitoring heart rate.