The Comparative Study Between Bowel Preparation Method: 4L-split Dose of PEG Solution, Low-volume PEG Plus Ascorbic Acid Focusing on the Bowel Cleansing Efficacy, Patients' Affinity to Preparation Solution and Mucosal Injury

Inje University1 site in 1 country319 target enrollmentSeptember 2013

ConditionsColonoscopy

InterventionsColonoscopy after bowel cleansing

DrugsColonoscopy after bowel cleansing

Overview

Phase: Phase 3
Intervention: Colonoscopy after bowel cleansing
Conditions: Colonoscopy
Sponsor: Inje University
Enrollment: 319
Locations: 1
Primary Endpoint: Comparison of colon cleansing between the two solutions using Ottawa scale
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to compare the efficacy, acceptability and preparation-induced mucosal inflammation of PEG + ascorbic acid vs. PEG for colonoscopy.

Detailed Description

This was a prospective randomized single-blinded clinical trial of ambulatory patients to assess the efficacy of bowel preparation and preparation-induced mucosal inflammation. Endoscopists who were blinded to the preparation taken, assessed both bowel cleansing by using the Ottawa bowel preparation assessment tool and preparation-induced mucosal inflammation. Acceptability was assessed by questionnaire.

Registry

clinicaltrials.gov

Start Date

September 2013

End Date

January 2014

Last Updated

12 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Inje University

Responsible Party

Principal Investigator

Jongha Park

Inje University

Eligibility Criteria

Inclusion Criteria

•Patients who want colonoscopy purposing screening among adults between the age of 20\~65

Exclusion Criteria

•Under the age of 20, older than 65, pregnant or lactating women, intestinal obstruction, structural intestinal disease, hypothyroidism, gastrointestinal motility, renal failure, congestive heart failure, liver failure, electrolyte abnormalities, who refused research informed consent, inflammatory bowel disease, the obvious symptoms of the disease in patients with lower gastrointestinal (bloody stools, diarrhea, etc.)