Comparison the effect of fluoxetine and tamoxifen on the mastalgia
- Conditions
- mastalgia.mastalgia
- Registration Number
- IRCT20190128042525N1
- Lead Sponsor
- Rafsanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 74
Written consent
The person must remain in the region at least during the follow-up in the region
Reproductive ages between 18 to 50 years
Pre-menopause, mastalgia without obvious pathologic reason
The minimum score of the visual scale of pain is three
Pregnancy or breastfeeding or a decision to have a pregnancy
Contraindication of the use of the drugs mentioned (tamoxifen: pregnancy and lactation)
Thromboembolic / fluoxetine disorders: severe renal and hepatic failure
Patients with epilepsy who have uncontrolled seizures
History of breast cancer in self or first-degree relatives
A large lesion in the breast that needs surgery
Suspect of any malignancy
Galactorrhea
History of previous surgery
Hormone Therapy in the last three months
Taking Oral contraceptive pill
History of taking medication to treat breast pain
Any mental and psychiatric illness is associated with the use of related medications
Taking some medications (dopamine antagonists , Monoamine Oxidase Inhibitors (MAO), Warfarin, theophylline, hypnotics and progesterone)
Irregular menstruation
History of thromboembolism
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure pain. Timepoint: 4 weeks, 8 weeks and 12 weeks. Method of measurement: Visual Analogue Scale.
- Secondary Outcome Measures
Name Time Method Duration of illness. Timepoint: 3 months. Method of measurement: visual analogue scale.