ACTRN12611000550909尚未招募2 期
The effect of adrenergic blockade on hypermetabolism in patients post burn injury
Burns, Trauma & Critical Care Research Centre0 个研究点目标入组 26 人开始时间: 2011年5月31日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Acute burns patients
- •18years of age and over
- •30% total burns surface area,
- •Ready for discharge from intensive care, at a stage when they do not require inotropic support, are non septic, antibiotic free and capable of spontaneous breathing on a high flow humidifier
排除标准
- •Concomitant multi-trauma,
- •A premorbid history of asthma or bronchospasm,
- •Peripheral arterial disease,
- •Systolic blood pressure<100mmHg or mean arterial pressure of < 65mmHg,
- •Heart rate<60bpm,
- •Heart block on ECG,
- •Previous use of beta blockers before the burn injury, or previous prescription for greater than 24 hours within the preceding 24 hours,
- •Allergic disorders
- •Any cardiovascular conditions (hypertension, coronary artery disease, left ventricular systolic impairment, pulmonary hypertension, right ventricular impairment, sick sinus syndrome, heart block),
- •Renal or hepatic impairment,
- •Hyperthyroidism,
- •Previous depressive illness
- •Compassionate care only
研究者
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