Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Phase 2
Not yet recruiting
- Conditions
- Anesthesia, EndotrachealAnesthesia and Analgesia
- Interventions
- Registration Number
- NCT06382831
- Lead Sponsor
- Indonesia University
- Brief Summary
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia. This study aim to compare the effect of opioid free versus opioid balanced anesthesia in ophthalmology surgery
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
- Physical status of ASA 1-2
- Undergo elective ophthalmology surgery under general anesthesia with laryngeal mask insertion
- BMI 17.5-34.9
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Exclusion Criteria
- Allergy to study drugs
- Baseline heart rate < 70 beat per minute or systolic blood pressure < 100 mmHg
- Will undergo regional block
- Operation lasting for > 4 hours or < 90 minutes
- Consumes opioid routinely prior to operation
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control Fentanyl - Opioid free anesthesia Dexmedetomidine -
- Primary Outcome Measures
Name Time Method Time to laryngeal mask exertion Intraoperative Measured from the last surgical knot to LMA exertion
Adverse effect 24 hours Severe changes in hemodynamics, including severe bradycardia, tachycardia, hypotension, hypertension, desaturation
Postoperative nausea and vomiting (PONV) 24 hours Incidence of PONV
Pain score 24 hours Pain score assessed with numerical rating scale (0-10) where higher value corresponds to more pain experienced by the patient
- Secondary Outcome Measures
Name Time Method