Implementation and Assessment of Ventilator Associated Pneumonia bundle strategy to prevent ventilator associated pneumonia in Neonatal Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 450
- 试验地点
- 1
- 主要终点
- To evaluate the incidence of VAP pre and post implementation of VAPB
研究概览
简要总结
To reduce the incidence of VAP and reduce the associated morbidity and mortality.
Aim of the study is to Implement and Assess ventilator associated pneumonia in Neonatal intensive care unit. The study will be conducted between october 2018- March 2019.
All neonates admitted to NICU during study period and utilized mechanical ventilation for ≥ 48 hours.
It is a time dependent study with three phases, Phase 1, Phase 2 and Phase 3 wherein Phase 1 will assessed to check the incidence rate of VAP in mechanically ventilated newborns, to check the adherence of VAP bundle and debriefing if any errors in practice, The observations will be documented by the primary investigator.
In phase 2, “VAP prevention bundle will be tailored according to common errors found out in Phase I and include common evidence-based practices recommended by previous studies and agencies. We will be performing education session to discuss evidences about the pathogenesis, risk factors, danger of VAP and its sequel and the need for VAP bundle. Training and re-training campaigns will be performed for each VAP bundle’s item.
Phase 3 is a post VAP bundle implementation phase, re-evaluation of VAP rate to assess the efficacy of the infection control bundle.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 1.00 Day(s) 至 30.00 Day(s)（—）
- 性别
- All
入选标准
- •All neonates admitted to NICU during study period and utilized mechanical ventilation for ≥ 48 hours.
排除标准
- •Neonates who will be empirically started on antibiotics before mechanical ventilation -Out-hospital intubations.
结局指标
主要结局
To evaluate the incidence of VAP pre and post implementation of VAPB
时间窗: Before and after implementation of VAP Bundle
次要结局
- To assess the effect of each bundle component on the VAP incidence(The correlation between full adherence to the VAPB and VAP incidence)