NL-OMON52395招募中不适用
Effects of discontinuation of levothyroxine treatment in older adults: a self-controlled study. - RELEASE
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 415
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Community dwelling patients and nursing home patients aged 60 and over using
- •levothyroxine continuously for a minimum of 1 year at a stable dose.
排除标准
- •- Last measurement of TSH (thyroid stimulating hormone) >=10 mU/L during
- •levothyroxine treatment
- •- A history of thyroidectomy, radioactive iodine treatment, neck irradiation,
- •congenital hypothyroidism or secondary hypothyroidism
- •- Concurrent amiodarone or lithium use
- •- Concurrent use of liothyronine, thiamazole, carbimazole or propylthiouracil.
- •- Patients using a dose of more than 150 mcg levothyroxine per day
- •- Diagnosis of heart failure NYHA grade IV
- •- Diagnosis of dementia
- •- Incapacitated adults
- •- Life-expectancy of less than 6 months
- •- Participation in ongoing trials of therapeutic interventions
- •- Persons that plan to move out of the region in which the study is being
- •conducted in the next months
研究者
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