Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair

Phase 4

Terminated

• Conditions: Duration of Pain Relief
• Interventions: Drug: dexamethsone; Drug: Bupivacaine

• Registration Number: NCT01756560
• Lead Sponsor: University of Chicago

Brief Summary

Anterior cruciate ligament reapair is a painful procedure. Single shot femoral and sciatic nerve block only last 12-16 hrs. Since dexamethasone prolongs brachial plexus block, using it in lower extremity blocks will prolong the analgesia to provide better outpatient pain relief after surgery at home.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-12-20
• Study First Submitted QC: 2012-12-20
• Study First Posted: 2012-12-27
• Study Start: 2013-01
• Primary Completion: 2015-01
• Study Completion: 2015-01
• Results First Submitted: 2016-06-16
• Status Verified: 2019-04
• Results First Submitted QC: 2019-04-22
• Last Update Submitted: 2019-04-22
• Results First Posted: 2019-05-14
• Last Update Posted: 2019-05-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

• age 18-75, no contraindication to regional anesthesia

Exclusion Criteria

• peripheral neuropathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Dexamethasone	dexamethsone	Bupivacaine mixed with dexamethasone will be used to block femoral and sciatic nerve
control	Bupivacaine	in this group, plain bupivacaine will be used to block femoral and sciatic nerve
Dexamethasone	Bupivacaine	Bupivacaine mixed with dexamethasone will be used to block femoral and sciatic nerve

Primary Outcome Measures

Name	Time	Method
Analgesia Duration	72 hours

Trial Locations

Locations (1)

University of Chicago Medical Center; 🇺🇸 Chicago, Illinois, United States