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Assessment of the Efficacy of Vitamin D-fortified Oil in Healthy Adults

Not Applicable
Completed
Conditions
Healthy
Registration Number
NCT03826654
Lead Sponsor
National Nutrition and Food Technology Institute
Brief Summary

The aim of this study is to evaluate the efficacy of daily intake of fortified sunflower oil with vitamin D on serum 25-hydroxyvitamin D level, glycemic and lipidemic status in healthy subjects compared to plain oil.

Detailed Description

Sixty apparently healthy subjects will be selected. Participants who are receiving vitamin D, calcium or omega-3 supplements within the last three months will be excluded. Subjects will be assigned randomly to one of the two intervention groups: 1.fortified sunflower oil, 2. plain bread+vitamin D supplements,3. plain bread+placebo. Each participant will consume 50 g of oil every day for 2 months.

At the first and last visits, dietary and laboratory assessments will be performed for all subjects. Primary outcomes are the improvement in vitamin D status and secondary outcome is the improvement of glycemic and lipidemic markers and prevention of problems related to hypovitaminosis D.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • 20 to 60 years
  • healthy subjects
  • no receiving vitamin D or omega-3 supplement in past 3 months
Exclusion Criteria
  • receiving vitamin D or omega-3 supplement during the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
25-hydroxyvitamin D (nmol/L)8 weeks
Secondary Outcome Measures
NameTimeMethod
serum glucose (mg/dL)8 weeks
serum total cholesterol (mg/dL)8 weeks
serum triglyceride (mg/dL)8 weeks
serum LDL8 weeks
serum HDL8 weeks
serum PTH (pg/mL)8 weeks

Trial Locations

Locations (1)

Laboratory of Nutrition Research, National Nutrition and Food Technology Research Institute (NNFTRI) and Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

🇮🇷

Tehran, Iran, Islamic Republic of

Laboratory of Nutrition Research, National Nutrition and Food Technology Research Institute (NNFTRI) and Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
🇮🇷Tehran, Iran, Islamic Republic of

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