Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates

Not Applicable

Completed

• Conditions: Exercise Recovery
• Interventions: Dietary Supplement: Carbohydrate; Dietary Supplement: Carbohydrate and protein ingestion; Dietary Supplement: Carbohydrate and caffeine ingestion

• Registration Number: NCT00975390
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The aim of the present study is to investigate the effect of added protein+leucine or caffeine to 1.2 g/kg/h CHO on the rate of post-exercise muscle glycogen re-synthesis in healthy, recreational athletes.

The investigators hypothesize that both interventions (the addition of caffeine or protein+leucine) will lead to higher glycogen re-synthesis compared to the ingestion of CHO only, and that the co-ingestion of protein and leucine will result in the highest muscle glycogen synthesis rates.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02
• Primary Completion: 2009-09
• Study Completion: 2009-09
• Study First Submitted: 2009-09-10
• Study First Submitted QC: 2009-09-10
• Study First Posted: 2009-09-11
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-13
• Last Update Posted: 2015-04-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 14

Inclusion Criteria

• male cyclists
• healthy
• BMI < 25

Exclusion Criteria

• female
• use of medication
• non cycling
• BMI > 25

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	Carbohydrate	Carbohydrate ingestion
2	Carbohydrate and protein ingestion	Carbohydrate and protein ingestion
3	Carbohydrate and caffeine ingestion	Carbohydrate and caffeine ingestion

Primary Outcome Measures

Name	Time	Method
Muscle glycogen synthesis rates	6 hours

Secondary Outcome Measures

Name	Time	Method
Glycogen synthase activity, plasma glucose, insulin, free fatty acids and epinephrine responses	6 hours

Trial Locations

Locations (1)

Maastricht University; 🇳🇱 Maastricht, Netherlands