Caffein Consumption and Response Inhibition

Not Applicable

Completed

• Conditions: Eating Behavior; Obesity
• Interventions: Drug: Placebo; Drug: Caffeine

• Registration Number: NCT01815203
• Lead Sponsor: Uppsala University

Brief Summary

With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy levels.

One of the factors that is potentially important in response inhibition is caffeine.

The aim is to assess the direct effects of caffeine on response inhibition, using a No Go/Go-task. We will also assess whether the presentation of food cues, i.e. as words or as pictures, modulate response inhibition different in restrained vs. non-restrained eaters.

Detailed Description

In a blinded, randomized cross-over design, participants will receive either a capsule with caffeine or placebo at two separate occasions whereupon study tasks will be performed.

Study Timeline

• Study Start: 2013-03
• Study First Submitted: 2013-03-18
• Study First Submitted QC: 2013-03-18
• Study First Posted: 2013-03-20
• Primary Completion: 2013-07
• Study Completion: 2013-08
• Status Verified: 2013-09
• Last Update Submitted: 2013-09-23
• Last Update Posted: 2013-09-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 21

Inclusion Criteria

• Only males
• 18 ≤ 35 years
• Healthy (self rated)
• Used to drink caffeine
• Used to eat breakfast regularly (≥ 5 times a week).
• Non-smokers

Exclusion Criteria

• BMI outside the range of 18,5 ≤ 25
• hypersensitivity for the ingredients of the foods under study
• being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea
• Presence of any chronically disease and/or treatment with medication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	Administration of placebo (one gelatin capsule containing starch) with subsequent cognitive tasks and food test.
Caffeine	Caffeine	Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test.

Primary Outcome Measures

Name	Time	Method
Inhibition control	20 min	Measurement inhibition control via a computer test (NoGo-Go task.

Secondary Outcome Measures

Name	Time	Method
Food test	20 min	Measure of participants food intake.

Trial Locations

Locations (1)

Uppsala University; 🇸🇪 Uppsala, Sweden