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Caffeine and Resistance Training in Young Adults

Not Applicable
Completed
Conditions
Caffeine and Resistance Training
Interventions
Dietary Supplement: Caffeine plus Resistance training
Other: Placebo + Resistance training
Registration Number
NCT06610136
Lead Sponsor
University of Alcala
Brief Summary

Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effect of this supplement on neuromuscular adaptations to strength training.

Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to strength training.

Objectives: The present study aims to analyze the effects of acute and chronic caffeine intake on neuromuscular adaptations to strength training, according to sex (men vs. women) and type of exercise (bench press vs. squat), as well as on fatigue resistance during repeated sprints, fatigue perception, mood state, reaction time, diet, and potential side effects.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
48
Inclusion Criteria
  • Age between ≥ 18 and ≤ 35 years.
  • Body mass index (BMI) < 25 kg/m².
  • Physically active subjects (>150 min/week of moderate exercise).
  • Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
  • Participants capable of performing the tests.
Exclusion Criteria
  • History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
  • Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
  • Body mass index (BMI) > 25 kg/m².
  • Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
  • Performing strenuous exercise within 48 hours prior to the tests.
  • Failing to replicate the same food intake on the two experimental days.
  • Consuming caffeine after 6 PM on the day prior to training or testing.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Caffeine - MalesCaffeine plus Resistance training-
Placebo - MalesPlacebo + Resistance training-
Caffeine - FemalesCaffeine plus Resistance training-
Placebo - FemalesPlacebo + Resistance training-
Primary Outcome Measures
NameTimeMethod
Mean velocity at different %1RMThrough study completion, an average of 12 weeks

Measuring bar mean velocity desplacement during bench press and back squat exercises.

Peak velocity at different %1RMThrough study completion, an average of 12 weeks

Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.

Mean power output at different %1RMThrough study completion, an average of 12 weeks

Measuring during bench press and back squat exercises.

Peak power output and time to reach peak power output at different %1RMThrough study completion, an average of 12 weeks

Measuring during bench press and back squat exercises.

Number of repetitions performed at 65%1RM until task failureThrough study completion, an average of 12 weeks

In bench press and back squat exercises

Bar velocity deplacement performed in 1 set at 65%1RM until task failureThrough study completion, an average of 12 weeks

In bench press and back squat exercises

Power output generated in 1 set at 65%1RM until task failureThrough study completion, an average of 12 weeks

In bench press and back squat exercise

Secondary Outcome Measures
NameTimeMethod
Resting Metabolic Rate (RMR)Through study completion, an average of 12 weeks

Kcal at rest using a metabolic chart.

Maximal Fat Oxidation Rate (MFO)Through study completion, an average of 12 weeks

g/min using a metabolic chart.

Fat massThrough study completion, an average of 12 weeks

Using electrical bioimpedance (kg and % of body mass)

Fat-free massThrough study completion, an average of 12 weeks

Using electrical bioimpedance (kg and % of body mass)

Physical activity (METs-min/wk)Through study completion, an average of 12 weeks

Using IPAQ

Dietary (g/kg of macronutrients)Through study completion, an average of 12 weeks

Using a 24-total recall

Mood stateThrough study completion, an average of 12 weeks

Mood. Participants graded a set of 29 items related to the mood on a Likert scale from 0 (not at all) to 4 (extremely) in reply to the question;How do you feel at this moment?; to assess six scales: tension, depression, anger, vigor, fatigue and confusion.

Adverse effectsThrough study completion, an average of 12 weeks

Adverse effects. perception of power, endurance, energy and exertion, as well as heart, muscular and gastrointestinal discomfort.

Trial Locations

Locations (1)

Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

🇪🇸

Alcalá de Henares, Madrid, Spain

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